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Spyre Therapeutics, Inc.

Data quality: 100%
SYRE
NASDAQ Healthcare Biotechnology
$42.76
▲ $1.51 (3.66%)
Mkt Cap: 2.58B
Day Range
$41.73 $44.08
52-Week Range
$10.91 $45.76
Volume
727,593
50D / 200D Avg
$37.13 / $24.94
Prev Close
$41.25

Price History

Financial Trends

Peer Comparison

vs Healthcare sector median (626 peers)

Metric Stock Sector Median
P/E -16.6 0.4
P/B 3.6 2.9
ROE % -25.2 3.8
Net Margin % 3.9
Rev Growth 5Y % 10.0
D/E 0.0 0.2

Key Takeaways

Debt/Equity of 0.00 — conservative balance sheet
Negative free cash flow of -169.25M

Growth

Revenue Growth (5Y)
N/A
Revenue (1Y)N/A
Earnings (1Y)N/A
FCF Growth (3Y)N/A

Quality

Return on Equity
-25.17%
ROIC-21.97%
Net MarginN/A
Op. MarginN/A

Safety

Debt / Equity
0.00
Current Ratio13.25
Interest Coverage0.00

Valuation

P/E Ratio
-16.64
P/B Ratio3.61
EV/EBITDAN/A
Dividend Yield0.00%

All Fundamental Metrics

Growth
Revenue Growth (1Y) N/A Revenue Growth (3Y) N/A
Earnings Growth (1Y) N/A Earnings Growth (3Y) N/A
Revenue Growth (5Y) N/A Earnings Growth (5Y) N/A
Profitability
Revenue (TTM) 0.0 Net Income (TTM) -155.20M
ROE -25.17% ROA -19.95%
Gross Margin N/A Operating Margin N/A
Net Margin N/A Free Cash Flow (TTM) -169.25M
ROIC -21.97% FCF Growth (3Y) N/A
Safety
Debt / Equity 0.00 Current Ratio 13.25
Interest Coverage 0.00 Dividend Yield 0.00%
Valuation
P/E Ratio -16.64 P/B Ratio 3.61
P/S Ratio N/A PEG Ratio 1.94
EV/EBITDA N/A Dividend Yield 0.00%
Market Cap 2.58B Enterprise Value 2.50B

Income Statement

Annual, most recent first

Income statement data, annual, most recent first
Metric FY2025 FY2024 FY2023 FY2022 FY2021
Revenue 0.0 0.0 886,000.0 2.33M 18.74M
Net Income -155.20M -208.02M -338.79M -83.82M -65.80M
EPS (Diluted) -1.98 -3.18 -46.15 -24.86 -25.02
Gross Profit -171.65M 0.0 886,000.0 2.33M 18.74M
Operating Income -209.56M -208.57M -242.30M -84.78M -65.65M

Balance Sheet

Annual, most recent first

Balance sheet data, annual, most recent first
Metric FY2025 FY2024 FY2023 FY2022 FY2021
Total Assets 777.78M 608.48M 341.86M 71.14M 109.93M
Total Liabilities 62.55M 90.68M 157.84M 20.84M 25.99M
Shareholders' Equity 715.24M 517.80M 184.02M 50.31M 83.94M
Total Debt 0.0 0.0 0.0 4.63M 5.06M
Cash & Equivalents 85.72M 89.42M 188.89M 34.86M 15.14M
Current Assets 777.78M 608.47M 341.53M 62.26M 98.89M
Current Liabilities 58.69M 54.06M 31.98M 14.66M 20.14M