| 1 |
LLY
|
Eli Lilly and Company |
8.71% |
24,753 |
18.89 M |
| 2 |
ISRG
|
Intuitive Surgical Inc. |
4.79% |
23,215 |
10.38 M |
| 3 |
ARGX
|
argenx SE |
4.64% |
13,651 |
10.07 M |
| 4 |
SYK
|
Stryker Corporation |
4.61% |
27,071 |
10.01 M |
| 5 |
UNH
|
UnitedHealth Group Incorporated |
4.12% |
25,907 |
8.95 M |
| 6 |
TMO
|
Thermo Fisher Scientific Inc. |
3.82% |
17,086 |
8.29 M |
| 7 |
ABBV
|
AbbVie Inc. |
3.40% |
31,882 |
7.38 M |
| 8 |
ALNY
|
Alnylam Pharmaceuticals Inc. |
3.35% |
15,931 |
7.26 M |
| 9 |
INSM
|
Insmed Incorporated |
3.09% |
46,572 |
6.71 M |
| 10 |
GILD
|
Gilead Sciences Inc. |
2.72% |
53,127 |
5.90 M |
| 11 |
DHR
|
Danaher Corporation |
2.49% |
27,272 |
5.41 M |
| 12 |
BSX
|
Boston Scientific Corporation |
2.43% |
53,962 |
5.27 M |
| 13 |
VRTX
|
Vertex Pharmaceuticals Incorporated |
2.42% |
13,377 |
5.24 M |
| 14 |
AZN US
|
AstraZeneca PLC |
2.31% |
65,286 |
5.01 M |
| 15 |
6160 HK
|
BeOne Medicines Ltd |
1.94% |
157,998 |
4.22 M |
| 16 |
CI
|
The Cigna Group |
1.66% |
12,512 |
3.61 M |
| 17 |
REGN
|
Regeneron Pharmaceuticals Inc. |
1.57% |
6,059 |
3.41 M |
| 18 |
ASND
|
Ascendis Pharma A/S |
1.55% |
16,889 |
3.36 M |
| 19 |
PEN
|
Penumbra Inc. |
1.38% |
11,805 |
2.99 M |
| 20 |
THC
|
Tenet Healthcare Corporation |
1.13% |
12,106 |
2.46 M |
| 21 |
RNA US
|
Avidity Biosciences Inc. |
1.06% |
52,894 |
2.30 M |
| 22 |
CVS
|
CVS Health Corporation |
1.03% |
29,671 |
2.24 M |
| 23 |
ELV
|
Elevance Health Inc. |
1.00% |
6,740 |
2.18 M |
| 24 |
NTRA
|
Natera Inc. |
0.97% |
13,025 |
2.10 M |
| 25 |
HCA
|
HCA Healthcare Inc. |
0.92% |
4,690 |
2.00 M |
| 26 |
UTHR
|
United Therapeutics Corporation |
0.85% |
4,407 |
1.85 M |
| 27 |
COR US
|
Cencora Inc. |
0.76% |
5,251 |
1.64 M |
| 28 |
DGX
|
Quest Diagnostics Incorporated |
0.75% |
8,512 |
1.62 M |
| 29 |
RVMD
|
Revolution Medicines Inc. |
0.71% |
32,896 |
1.54 M |
| 30 |
SRRK
|
Scholar Rock Holding Corporation |
0.71% |
41,151 |
1.53 M |
| 31 |
GH
|
Guardant Health Inc. |
0.69% |
23,937 |
1.50 M |
| 32 |
CNTA
|
Centessa Pharmaceuticals plc |
0.69% |
61,450 |
1.49 M |
| 33 |
BTSG
|
BrightSpring Health Services Inc. |
0.68% |
49,634 |
1.47 M |
| 34 |
IDXX
|
IDEXX Laboratories Inc. |
0.66% |
2,228 |
1.42 M |
| 35 |
SMMT
|
Summit Therapeutics Inc. |
0.65% |
68,527 |
1.42 M |
| 36 |
KYMR
|
Kymera Therapeutics Inc. |
0.65% |
24,802 |
1.40 M |
| 37 |
NBIX
|
Neurocrine Biosciences Inc. |
0.65% |
9,983 |
1.40 M |
| 38 |
CAH
|
Cardinal Health Inc. |
0.62% |
8,584 |
1.35 M |
| 39 |
PTGX
|
Protagonist Therapeutics Inc. |
0.61% |
20,042 |
1.33 M |
| 40 |
IONS
|
Ionis Pharmaceuticals Inc. |
0.58% |
19,250 |
1.26 M |
| 41 |
VEEV
|
Veeva Systems Inc. |
0.57% |
4,143 |
1.23 M |
| 42 |
SNY
|
Sanofi |
0.56% |
25,926 |
1.22 M |
| 43 |
ONC US
|
BeOne Medicines Ltd. |
0.53% |
3,404 |
1.16 M |
| 44 |
AKRO US
|
Akero Therapeutics Inc. |
0.53% |
24,412 |
1.16 M |
| 45 |
CRNX
|
Crinetics Pharmaceuticals Inc. |
0.51% |
26,745 |
1.11 M |
| 46 |
KRYS
|
Krystal Biotech Inc. |
0.51% |
6,206 |
1.10 M |
| 47 |
CYTK
|
Cytokinetics Incorporated |
0.46% |
18,234 |
1.00 M |
| 48 |
SLNO US
|
Soleno Therapeutics Inc. |
0.46% |
14,675 |
992,030.0 |
| 49 |
SOON SW
|
Sonova Holding AG |
0.43% |
3,406 |
934,286.67 |
| 50 |
NUVL
|
Nuvalent Inc. |
0.41% |
10,180 |
880,366.4 |
| 51 |
EXAS
|
Exact Sciences Corporation |
0.40% |
16,021 |
876,508.91 |
| 52 |
VERA
|
Vera Therapeutics Inc. |
0.40% |
30,014 |
872,206.84 |
| 53 |
MRUS US
|
Merus N.V. |
0.40% |
9,185 |
864,767.75 |
| 54 |
EHC
|
Encompass Health Corporation |
0.40% |
6,760 |
858,655.2 |
| 55 |
INCY
|
Incyte Corporation |
0.37% |
9,477 |
803,744.37 |
| 56 |
RYTM
|
Rhythm Pharmaceuticals Inc. |
0.37% |
7,878 |
795,599.22 |
| 57 |
CGON
|
CG Oncology Inc. |
0.37% |
19,744 |
795,288.32 |
| 58 |
MDGL
|
Madrigal Pharmaceuticals Inc. |
0.36% |
1,706 |
782,473.96 |
| 59 |
IMNM
|
Immunome Inc. |
0.35% |
65,604 |
768,222.84 |
| 60 |
CAI
|
Caris Life Sciences Inc. |
0.35% |
24,932 |
754,193.0 |
| 61 |
PCVX
|
Vaxcyte Inc. |
0.33% |
19,884 |
716,221.68 |
| 62 |
AGIO
|
Agios Pharmaceuticals Inc. |
0.33% |
17,752 |
712,565.28 |
| 63 |
ACLX
|
Arcellx Inc. |
0.33% |
8,646 |
709,836.6 |
| 64 |
RVTY
|
Revvity Inc. |
0.33% |
8,058 |
706,283.7 |
| 65 |
IMCR
|
Immunocore Holdings plc |
0.32% |
19,369 |
703,675.77 |
| 66 |
QURE
|
uniQure N.V. |
0.32% |
11,927 |
696,178.99 |
| 67 |
IQV
|
IQVIA Holdings Inc. |
0.32% |
3,659 |
694,990.46 |
| 68 |
ROIV
|
Roivant Sciences Ltd. |
0.31% |
44,415 |
671,998.95 |
| 69 |
4519 JP
|
Chugai Pharmaceutical Co. Ltd. |
0.30% |
14,800 |
656,150.22 |
| 70 |
AXSM
|
Axsome Therapeutics Inc. |
0.29% |
5,249 |
637,491.05 |
| 71 |
BEAM
|
Beam Therapeutics Inc. |
0.28% |
24,779 |
601,386.33 |
| 72 |
ALHC
|
Alignment Healthcare Inc. |
0.27% |
34,030 |
593,823.5 |
| 73 |
RAPP
|
Rapport Therapeutics Inc. |
0.27% |
19,989 |
593,673.3 |
| 74 |
ZLAB
|
Zai Lab Limited |
0.27% |
17,391 |
589,380.99 |
| 75 |
IRON US
|
Disc Medicine Inc. |
0.27% |
8,893 |
587,649.44 |
| 76 |
ABVX
|
Abivax SA |
0.26% |
6,687 |
567,726.3 |
| 77 |
ALKS
|
Alkermes Public Limited Company |
0.25% |
18,181 |
545,430.0 |
| 78 |
CELC
|
Celcuity Inc. |
0.25% |
10,839 |
535,446.6 |
| 79 |
DNLI
|
Denali Therapeutics Inc. |
0.24% |
36,384 |
528,295.68 |
| 80 |
MOH
|
Molina Healthcare Inc. |
0.24% |
2,754 |
527,005.44 |
| 81 |
APGE US
|
Apogee Therapeutics Inc. |
0.24% |
13,010 |
516,887.3 |
| 82 |
MCK
|
McKesson Corporation |
0.24% |
660 |
509,876.4 |
| 83 |
RPRX US
|
Royalty Pharma plc |
0.23% |
14,388 |
507,608.64 |
| 84 |
DXCM
|
DexCom Inc. |
0.23% |
7,526 |
506,424.54 |
| 85 |
BCAX
|
Bicara Therapeutics Inc. |
0.22% |
29,778 |
470,194.62 |
| 86 |
BIIB
|
Biogen Inc. |
0.22% |
3,352 |
469,548.16 |
| 87 |
TARS
|
Tarsus Pharmaceuticals Inc. |
0.21% |
7,834 |
465,574.62 |
| 88 |
RARE
|
Ultragenyx Pharmaceutical Inc. |
0.21% |
15,246 |
458,599.68 |
| 89 |
PRCT
|
Procept Biorobotics Corporation |
0.19% |
11,288 |
402,868.72 |
| 90 |
CLDX
|
Celldex Therapeutics Inc. |
0.19% |
15,561 |
402,563.07 |
| 91 |
ICLR
|
Icon Public Limited Company |
0.18% |
2,228 |
389,900.0 |
| 92 |
BBIO
|
BridgeBio Pharma Inc. |
0.18% |
7,500 |
389,550.0 |
| 93 |
PHVS
|
Pharvaris N.V. |
0.17% |
14,975 |
373,626.25 |
| 94 |
MBX
|
MBX Biosciences Inc. |
0.17% |
21,168 |
370,440.0 |
| 95 |
TEM
|
Tempus AI Inc. |
0.17% |
4,477 |
361,338.67 |
| 96 |
BIO
|
Bio-Rad Laboratories Inc. |
0.16% |
1,234 |
346,001.26 |
| 97 |
BHVN US
|
Biohaven Ltd. |
0.16% |
22,946 |
344,419.46 |
| 98 |
HTFL
|
Heartflow Inc. |
0.15% |
9,606 |
323,337.96 |
| 99 |
PRAX US
|
Praxis Precision Medicines Inc. |
0.15% |
6,057 |
321,021.0 |
| 100 |
ORIC
|
ORIC Pharmaceuticals Inc. |
0.14% |
25,630 |
307,560.0 |
| 101 |
WGS
|
GeneDx Holdings Corp. |
0.14% |
2,730 |
294,130.2 |
| 102 |
TECH
|
Bio-Techne Corporation |
0.13% |
5,000 |
278,150.0 |
| 103 |
KMTS
|
Kestra Medical Technologies Ltd |
0.13% |
11,456 |
272,194.56 |
| 104 |
VRDN
|
Viridian Therapeutics Inc. |
0.11% |
11,500 |
248,170.0 |
| 105 |
JANX
|
Janux Therapeutics Inc. |
0.11% |
10,117 |
247,259.48 |
| 106 |
SYRE
|
Spyre Therapeutics Inc. |
0.11% |
14,141 |
237,003.16 |
| 107 |
RDNT
|
RadNet Inc. |
0.11% |
3,000 |
228,630.0 |
| 108 |
CNC
|
Centene Corporation |
0.11% |
6,400 |
228,352.0 |
| 109 |
GLUE
|
Monte Rosa Therapeutics Inc. |
0.10% |
29,932 |
221,796.12 |
| 110 |
4523 JP
|
Eisai Co. Ltd. |
0.10% |
6,400 |
216,209.93 |
| 111 |
RGEN
|
Repligen Corporation |
0.10% |
1,600 |
213,872.0 |
| 112 |
BCYC US
|
Bicycle Therapeutics plc |
0.09% |
25,602 |
198,159.48 |
| 113 |
GPCR
|
Structure Therapeutics Inc. |
0.09% |
6,977 |
195,356.0 |
| 114 |
ORKA
|
Oruka Therapeutics Inc. |
0.09% |
9,891 |
190,203.93 |
| 115 |
WVE
|
Wave Life Sciences Ltd. |
0.08% |
24,968 |
182,765.76 |
| 116 |
LENZ US
|
LENZ Therapeutics Inc. |
0.08% |
3,800 |
177,004.0 |
| 117 |
IDYA
|
IDEAYA Biosciences Inc. |
0.08% |
6,339 |
172,484.19 |
| 118 |
RLAY
|
Relay Therapeutics Inc. |
0.08% |
32,881 |
171,638.82 |
| 119 |
REPL
|
Replimune Group Inc. |
0.08% |
40,761 |
170,788.59 |
| 120 |
BBOT US
|
BridgeBio Oncology Therapeutics Inc. |
0.08% |
14,485 |
167,736.3 |
| 121 |
ACAD
|
Acadia Pharmaceuticals Inc. |
0.07% |
7,600 |
162,184.0 |
| 122 |
XNCR
|
Xencor Inc. |
0.07% |
13,179 |
154,589.67 |
| 123 |
ELVN
|
Enliven Therapeutics Inc. |
0.07% |
7,480 |
153,115.6 |
| 124 |
HIMS
|
Hims and Hers Health Inc. |
0.07% |
2,600 |
147,472.0 |
| 125 |
KYTX US
|
Kyverna Therapeutics Inc. |
0.07% |
24,113 |
144,678.0 |
| 126 |
BBNX US
|
Beta Bionics Inc. |
0.07% |
7,125 |
141,573.75 |
| 127 |
MIRM
|
Mirum Pharmaceuticals Inc. |
0.06% |
1,900 |
139,289.0 |
| 128 |
SION
|
Sionna Therapeutics Inc. |
0.06% |
4,726 |
138,991.66 |
| 129 |
DNTH
|
Dianthus Therapeutics Inc. |
0.06% |
3,302 |
129,933.7 |
| 130 |
ALEC US
|
Alector Inc. |
0.06% |
43,704 |
129,363.84 |
| 131 |
KOD
|
Kodiak Sciences Inc. |
0.06% |
7,500 |
122,775.0 |
| 132 |
IMRX US
|
Immuneering Corporation |
0.06% |
17,357 |
121,499.0 |
| 133 |
WAT
|
Waters Corporation |
0.06% |
400 |
119,924.0 |
| 134 |
MDWD US
|
MediWound Ltd |
0.05% |
6,487 |
116,895.74 |
| 135 |
URGN
|
UroGen Pharma Ltd. |
0.05% |
5,400 |
107,730.0 |
| 136 |
ALLO
|
Allogene Therapeutics Inc. |
0.05% |
81,376 |
100,906.24 |
| 137 |
MLTX
|
MoonLake Immunotherapeutics |
0.05% |
13,971 |
100,172.07 |
| 138 |
IMTX
|
Immatics N.V. |
0.04% |
10,404 |
88,642.08 |
| 139 |
NAMS US
|
NewAmsterdam Pharma Company N.V. |
0.04% |
2,900 |
82,476.0 |
| 140 |
VSTM US
|
Verastem Inc. |
0.04% |
9,100 |
80,353.0 |
| 141 |
RCKT US
|
Rocket Pharmaceuticals Inc. |
0.04% |
23,535 |
76,724.1 |
| 142 |
VYGR US
|
Voyager Therapeutics Inc. |
0.03% |
15,964 |
74,551.88 |
| 143 |
ALSEN FP
|
Sensorion |
0.03% |
182,870 |
73,643.99 |
| 144 |
CBIO US
|
Crescent Biopharma Inc. |
0.03% |
5,959 |
70,852.51 |
| 145 |
LBRX
|
LB Pharmaceuticals Inc |
0.03% |
4,390 |
69,318.1 |
| 146 |
IOVA
|
Iovance Biotherapeutics Inc. |
0.03% |
31,687 |
68,760.79 |
| 147 |
ANNX
|
Annexon Inc. |
0.03% |
22,109 |
67,432.45 |
| 148 |
TRDA
|
Entrada Therapeutics Inc |
0.03% |
11,625 |
67,425.0 |
| 149 |
AURA US
|
Aura Biosciences Inc. |
0.03% |
10,426 |
64,432.68 |
| 150 |
OBIO US
|
Orchestra Biomed Holdings Inc. |
0.02% |
13,354 |
33,117.92 |
| 151 |
DNA US
|
Ginkgo Bioworks Holdings Inc. |
0.01% |
1,971 |
28,737.18 |
| 152 |
PRLD US
|
Prelude Therapeutics Incorporated |
0.01% |
17,428 |
25,096.32 |
| 153 |
GBIO US
|
Generation Bio Co. |
0.01% |
3,769 |
23,066.28 |
| 154 |
CLYM US
|
Climb Bio Inc. |
0.01% |
9,200 |
18,492.0 |
| 155 |
CABA US
|
Cabaletta Bio Inc. |
0.00% |
2,887 |
6,755.58 |
| 156 |
RVMDW
|
Revolution Medicines Inc. |
0.00% |
4,502 |
1,350.6 |
| 157 |
WGSWW
|
GeneDx Holdings Corp. |
0.00% |
4,862 |
532.88 |
| 158 |
SLGCW
|
SomaLogic Inc. |
0.00% |
2,050 |
79.8 |